David Craig, a biotechnology founder and industry veteran, has released his book The New Rules of Biotech: A Founder’s Guide to Building Great Companies in hardcover and audiobook formats, joining the previously available paperback and Kindle editions. The book, published by D. Craig Consulting LLC, is now accessible in multiple formats to suit different reading preferences: hardcover ($29.99), paperback ($21.99), Kindle ($11.99), and audiobook on Google Play.
The book addresses a critical shift in the biotech landscape, arguing that the playbook from 2021 is no longer viable. With capital more expensive, the FDA raising its bar, and the Inflation Reduction Act altering drug economics before approval, Craig offers a practical operating manual for building companies under these new conditions. He draws on his experience founding and running a preclinical biotech to cover topics such as choosing between platforms and assets, selecting affordable modalities, raising seed rounds against milestones, and leveraging non-dilutive capital strategically.
The narrative follows the drug development process from IND-enabling work through CMC and clinical decisions, then into term sheets, board dynamics, business development, and exit strategies like acquisitions and IPOs. Each chapter includes takeaways for operators and separate insights for investors and advisors, making the book useful for both sides of the table.
Craig’s motivation for founding his company stemmed from a family connection to RYR-1 related congenital muscular dystrophy, a rare genetic muscle disease. This personal connection underscores the book’s argument that biotech company building carries a responsibility beyond financial returns.
‘Founders and operators take in ideas in different ways,’ Craig said. ‘The hardcover is there for the people who want a durable copy on the desk, the paperback and Kindle for everyone else, and the audiobook on Google Play for those who prefer to listen on the move. The message is the same across all of them: build for the market that exists now, not the one that existed in 2021.’
The book is available for purchase on Amazon and Google Play. David Craig is the founder and CEO of Sarcomatrix Therapeutics Corp. and principal of D. Craig Consulting LLC, with decades of experience in pharmaceuticals and biotechnology since 1986.
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